10 Foolproof Ways to Stop Wellbutrin Without Gaining Weight!

Easy Ways to Stop Wellbutrin Without Gaining Weight and Stay Healthy! Discover Effective Strategies for Coming Off Wellbutrin without Weight Gain. Wellbutrin (bupropion) is a popular medication for treating depression and helping with quitting smoking. But many people worry about gaining weight when they stop taking it. This blog post will give you simple tips to stop Wellbutrin without gaining weight while staying fit and healthy. By following these effective suggestions, you can have a smooth transition and take care of your overall well-being.

Understanding Wellbutrin and Weight Gain

Before we look at ways to stop Wellbutrin without gaining weight, let’s briefly talk about how Wellbutrin can affect your weight. While weight gain is not a common side effect of Wellbutrin, some people may experience changes in appetite or metabolism during their treatment. Actually, everyone responds differently to medication, and factors like lifestyle, genetics, and existing conditions can influence weight changes.

Wellbutrin, also known as bupropion, is an antidepressant used to treat depression. It is also used to help people quit smoking, known as Zyban. It’s important to consult your doctor before stopping Wellbutrin because it affects brain chemistry. The best way to stop Wellbutrin is to gradually reduce the dosage with your doctor’s guidance. Pay attention to any side effects that may occur during this process.

how to stop wellbutrin without gaining weight
How to stop Wellbutrin without gaining weight?

How Weight gain after stopping Wellbutrin: Stopping Wellbutrin may lead to weight gain after initially helping with weight loss. This is because Wellbutrin, or Bupropion, affects chemicals in the brain that regulate weight. When the medication is discontinued, the balance of these chemicals can change, potentially causing weight gain to resume.

Does Wellbutrin Cause Weight Loss? If you’re struggling with obesity and want to shed some extra pounds, Wellbutrin SR might be a helpful tool when used alongside a healthy diet and exercise routine. Taking either 300 or 400 milligrams of Wellbutrin SR each day for six months (24 weeks) can help you lose 7% or 10% of your body weight, respectively. Even better, if you continue taking the medication for another six months (24 weeks), you can maintain this weight loss. So, it’s a potential option to consider in your weight loss journey!

Talk to Your Healthcare Provider

The first step in stopping Wellbutrin without gaining weight is to consult your healthcare provider. They will give you personalized advice based on your medical history, current dosage, and overall well-being. Your healthcare provider may recommend gradually reducing your medication or trying an alternative treatment. Their guidance will be valuable throughout the process.

  • Have a conversation with your doctor.
  • Explain why you want to stop taking Wellbutrin.
  • Let your doctor know if you feel you no longer need medication, experience bothersome side effects, or think the medication isn’t effective after waiting for eight weeks.
  • This information will assist your doctor in making an informed decision about whether it’s appropriate for you to discontinue Wellbutrin.

How to Stop Wellbutrin without Gaining Weight

1. Taper based on your doctor’s schedule

Follow your doctor’s tapering schedule for stopping Wellbutrin. The length of time to taper off Wellbutrin depends on your medication history and prescribed dose. Your doctor will determine the best tapering plan for you.

  • The usual target dose for Wellbutrin is 300 mg per day, but your specific prescription may vary. Always follow your prescribed dosages.
  • Typically, for patients on a 300 mg daily dose, the reduction schedule involves decreasing to 200 mg first and then reducing by 50 mg in subsequent reductions. Your doctor will closely monitor your response to determine the best reduction schedule for you.
  • Tapering off Wellbutrin can take weeks to months, depending on the individual.
  • If you have regular tablets, your doctor may advise cutting them to adjust the dose. However, extended-release or sustained-release tablets cannot be cut.
  • Tapering these formulations may involve prescribing lower dose tablets or taking the same dose at longer intervals, such as every other day.
  • Keep track of your tapering schedule by writing down the dates and dosage changes.

2. Document any effects you experience

Take note of any effects you experience while tapering off Wellbutrin. Even during the tapering process, you may still have the discontinuation symptoms mentioned earlier. If you experience any of these symptoms, keep track of them and discuss them with your doctor.

  • Discontinuation symptoms start quickly, gradually improve over one to two weeks, and involve more physical complaints. To distinguish between relapse and discontinuation symptoms, pay attention to when the symptoms begin, how long they last, and the type of symptoms.
  • Although discontinuation symptoms with Wellbutrin are not common, there is a higher risk of side effects if you discontinue without starting a new antidepressant with a similar pharmacodynamic profile.
  • It’s possible to experience a relapse of depression when discontinuing therapy. Keep your doctor informed about how you’re feeling and if you have concerns about a relapse.
  • Relapse symptoms develop gradually over two to three weeks and worsen over two to four weeks. If any symptoms persist for more than one month, contact your doctor.

Stay in touch with your doctor and keep them informed about your progress. Whether you experience symptoms or not, it’s important to update your doctor.

Let your doctor know if you have any concerns or notice any relapse symptoms. Your doctor will continue to monitor you for a few months after you stop taking Wellbutrin.

3. Focus on Eating Well

Stopping Wellbutrin gives you a chance to reevaluate your eating habits and make positive changes. Eat a balanced diet that includes fruits, vegetables, lean proteins, whole grains, and healthy fats. Practice portion control and mindful eating to avoid overeating. Make sure you consume the right number of calories to meet your energy needs without going overboard.

Make changes to your diet. Eating healthy can have a positive impact on your overall well-being. Specifically, including omega-3 fatty acids in your diet can be beneficial as an additional treatment for depression. You can find omega-3 fatty acids in foods like kale, spinach, flaxseeds, walnuts, and fatty fish such as salmon. They are also available in over-the-counter fish oil gelatin capsules. Research has shown that doses of omega-3 fatty acids between 1 to 9 grams can be effective in mood disorders, but recent evidence suggests that lower doses within that range are more beneficial.

Also Read – Burn Fat Overnight While You Sleep: The Best Tummy Slimming Cream.

4. Get Active Regularly

Regular exercise is important for maintaining a healthy weight and overall well-being. It not only burns calories but also improves your mood and reduces the risk of weight gain. Find activities you enjoy, like brisk walking, jogging, cycling, swimming, or strength training. Aim for at least 150 minutes of moderate-intensity exercise each week.

So, it’s really important to exercise regularly. Research suggests that regular exercise can boost endorphins and neurotransmitters, which can potentially alleviate symptoms of depression. Aim for around 30 minutes of exercise per day.

5. Manage Stress

Stress can affect your weight, so it’s essential to focus on stress reduction techniques when stopping Wellbutrin. Try mindfulness, deep breathing exercises, yoga, or meditation to promote relaxation and emotional well-being. Engage in activities that bring you joy and help you cope with stress, such as hobbies, spending time with loved ones, or pursuing creative endeavors.

Consider trying psychotherapy. Research shows that people who receive psychotherapy while discontinuing an antidepressant have a lower risk of relapse. Psychotherapy is a helpful approach for individuals with mental disorders, as it teaches strategies to cope with negative thoughts and behaviors. It equips people with tools to manage stress, anxiety, and improve overall well-being. There are various types of psychotherapy available, and the treatment plan will depend on the individual, the severity of the disorder, and other factors such as medication usage.

  • One effective type of psychotherapy is cognitive behavioral therapy (CBT), which aims to foster positive thinking and behavior changes. CBT focuses on current issues and finding practical solutions. A therapist assists in identifying unhelpful thoughts and beliefs, leading to behavioral changes. CBT is particularly beneficial for treating depression.
  • Other therapy options include interpersonal therapy, which improves communication patterns; family-focused therapy, which resolves family conflicts impacting the illness; and psychodynamic therapy, which enhances self-awareness. These options offer additional ways to address mental health concerns.
meditation can manage stress and stop wellbutrin without gaining weight
Meditation can manage stress and stop Wellbutrin without gaining weight

Meditation can help improve symptoms of depression and anxiety, according to a Johns Hopkins analysis of previous studies. Just thirty minutes of daily meditation may make a difference.
There are practical ways to practice meditation. You can repeat a mantra or a prayer, take time to focus on your breathing or reflect on what you have read.
There are different aspects of meditation to consider:

  • Focus: By concentrating on a specific object, image, or breath, you can free your mind from worry and stress.
  • Relaxed breathing: Taking slow, deep breaths using your diaphragm (making your belly rise when you inhale, not your chest) activates your parasympathetic nervous system, which has a calming effect.
  • Quiet setting: Finding a quiet place to meditate is important, especially for beginners, as it helps minimize distractions.

Also Read – Effective Ways to Lose Belly Fat.

6. Track Your Progress

Monitoring your progress is important during the transition off Wellbutrin. Regularly check your weight, but remember it’s just one aspect of your overall health. Pay attention to other indicators like energy levels, mood, and overall fitness. Consider using a journal or mobile app to record your meals, exercises, and emotions. It can give you insights and keep you motivated.

7. Seek Support

Coming off medication can be challenging physically and emotionally. Seek support from friends, family, or support groups who can understand and empathize with your journey. Share your concerns, successes, and setbacks with them. Additionally, consider consulting a registered dietitian, therapist, or counselor for professional guidance tailored to your needs.

When stopping Wellbutrin, it’s important to do it slowly. Gradually reduce your dose over a period of about two weeks. This is called tapering. Avoid stopping abruptly or going “cold turkey” as it can lead to more severe discontinuation symptoms. Note that the symptoms when discontinuing Wellbutrin may be different from those of other antidepressants.

Symptoms can start within hours to three days after stopping and may include:

  • Stomach issues like nausea, vomiting, diarrhea, or cramps.
  • Sleep problems such as insomnia or nightmares.
  • Balance problems like dizziness or feeling lightheaded.
  • Sensory or movement issues such as numbness, tingling, tremors, or coordination difficulties.
  • Feelings of irritability, agitation, or anxiety.

This group of symptoms is sometimes called “discontinuation syndrome.”

8. Stick to a consistent sleep schedule

Depression can disrupt sleep, so it’s important to practice good sleep habits.
Follow these tips for good sleep hygiene:

  • Go to bed and wake up at the same time every day.
  • Avoid stimulating activities before bedtime, like exercise, watching TV, or working on the computer.
  • Don’t consume alcohol or caffeine close to bedtime.
  • Avoid large meals and excessive liquids a few hours before bed.
  • Create a sleep-friendly environment: keep your room cool, dark, and quiet.
  • Associate your bed with sleep rather than other activities like reading or work.

9. Follow your doctor’s prescription when taking any new medications

If you’re stopping Wellbutrin due to side effects or inadequate control of depression, your doctor may prescribe a different antidepressant.

The choice of medication depends on various factors like patient preference, prior response, effectiveness, safety, tolerance, cost, side effects, and drug interactions.

If you had side effects or your depression wasn’t well-managed, your doctor might recommend:

  • Selective serotonin reuptake inhibitors (SSRIs) like Prozac (fluoxetine), Zoloft (sertraline), Paxil (paroxetine), Celexa (citalopram), or Lexapro (escitalopram).
  • Serotonin-norepinephrine reuptake inhibitors (SNRIs) such as Effexor (venlafaxine).
  • Tricyclic antidepressants (TCAs) like Elavil (amitriptyline).
  • Monoamine oxidase inhibitors (MAOIs) can also be considered, but only after waiting at least two weeks after discontinuing Wellbutrin.

10. Sample Schedule to Taper off Wellbutrin

Schedule to Taper off Wellbutrin

Before making any changes to your medication, it’s important to talk to your doctor. They can give you personalized advice and create a plan for gradually reducing your Wellbutrin dosage.

Tapering off Wellbutrin involves lowering your dose slowly over time. This helps your body adjust and reduces withdrawal symptoms. Your doctor will give you a schedule based on your needs.

Here’s a general example of a tapering schedule for Wellbutrin:

  • Week 1: Take your regular dose as prescribed.
  • Week 2: Reduce your daily dose by 25% (e.g., from 300 mg to 225 mg).
  • Week 3: Reduce your daily dose by another 25% (e.g., from 225 mg to 150 mg).
  • Week 4: Reduce your daily dose by another 25% (e.g., from 150 mg to 75 mg).
  • Week 5: Your doctor will guide you on either stopping the medication completely or decreasing the dose further before stopping.

Throughout the tapering process, pay attention to any changes in your symptoms and stay in touch with your doctor. They can provide support, monitor your progress, and adjust the schedule if needed. Remember, everyone’s experience is different, and your doctor will consider your individual situation when creating the plan.

Please consult your healthcare provider for professional advice tailored to your situation when tapering off Wellbutrin. After that, you can easily stop Wellbutrin without gaining weight.

Final Words

You can stop Wellbutrin without gaining weight by taking a holistic approach that includes nutrition, exercise, stress management, and support. By following these easy ways, you can have a smooth transition while prioritizing your health and fitness. Remember, everyone’s journey is unique, so be patient with yourself and celebrate small victories along the way. With the right strategies and mindset, you can successfully navigate this transition and maintain a healthy and active lifestyle.


Will I gain weight when I stop taking Wellbutrin?

It’s common to lose weight while on Wellbutrin and gain weight after stopping it. Wellbutrin, also known as bupropion, is a medication used for depression and as an aid to quit smoking. One of its side effects is weight loss, which some people find appealing.

When will I start losing weight on Wellbutrin?

The time it takes to lose weight on Wellbutrin can vary, but most individuals can expect to see results around eight weeks after starting the medication.

Is it difficult to stop taking Wellbutrin?

Stopping Wellbutrin suddenly can lead to withdrawal symptoms, including irritability, anxiety, sleep problems, and body aches. To avoid these symptoms, it’s recommended to gradually reduce the dosage before completely stopping the medication. Wellbutrin withdrawal symptoms can last for several months, as the underlying issues that led to drug addiction, such as trauma or mental disorders, may still need to be addressed. The experience of withdrawal from Wellbutrin can be challenging due to the potential for depression and suicidal thoughts.

What happens when I gradually stop taking Wellbutrin?

Most people don’t experience withdrawal symptoms or signs when they stop taking Wellbutrin. However, those who do may experience mild to moderate symptoms, including sweating, digestive problems (such as nausea and loss of appetite), and insomnia. Unusual dreams or nightmares may also occur.

How long does it take to gradually stop taking Wellbutrin?

Wellbutrin and its metabolites have longer half-lives compared to some other antidepressants. This means that withdrawal symptoms may not be as severe. In most cases, Wellbutrin withdrawal lasts around one to two weeks.

What is the most significant side effect of Wellbutrin?

Some people may experience bothersome side effects like headaches, nausea, and insomnia. In rare cases, Wellbutrin can actually cause serious side effects, such as suicidal thoughts or behaviors, especially when starting the medication or after dosage changes.

Why am I gaining weight on Wellbutrin?

Like other SNRIs and SSRIs, bupropion (Wellbutrin) can cause easy weight gain as it affects the levels of dopamine and norepinephrine, which are involved in controlling appetite and eating. Bupropion may increase the craving for carbohydrate-rich foods, such as desserts, legumes, and dairy products.


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