Intermittent Fasting Affects DNA Expression, Found in New Study

A recent study has found that intermittent fasting or only eating during specific times of the day can have a significant impact on DNA expression in mice. This type of fasting actually led to “profound” changes in genetic expression. So, this results in a reduced risk of obesity and inflammation. These findings actually suggest that intermittent fasting may have numerous health benefits. Intermittent fasting could be a potentially powerful tool for preventing and managing a range of diseases as per a recent study. So if you’re really looking to improve your overall health and wellness, consider giving actual intermittent fasting a try!

A recent study published in the Journal Cell Metabolism has shown the potential benefits of intermittent fasting. The study, which involved mice, found that feeding the mice only during certain blocks of time resulted in “profound” changes in gene expression. Nearly 80% of all genes were impacted in some way, leading to a range of health benefits including improved blood sugar regulation, decreased risk of obesity, and even a reversal of certain signs of aging.

Intermittent Fasting Found to Affect DNA Expression in New Study
Researchers find how time-restricted eating affects gene expression in areas of body, brain

Gene expression refers to the process by which the information in a gene is converted into a protein product by cellular machinery. Because proteins are really important and responsible for most cellular functions, including fat metabolism and immune response, even slight changes in gene expression can have a significant impact on the body. In this study, the researchers found that restricting the feeding times of the mice reshaped when and to what extent certain genes were expressed. For example, some organs were able to switch on the genes for regulating blood sugar when it was time to eat and repress them when it was time to fast.

These findings actually suggest that intermittent fasting may be a powerful tool for preventing and properly managing a range of diseases. This fasting may manage diabetes, heart disease and cancer. The researchers believe that their findings open the door for further research into how dietary interventions can impact our genes and overall health. While more research is needed to exactly confirm these findings in humans, the results of this study are certainly promising and provide further evidence of the potential benefits of intermittent fasting.

What is time-restricted eating?

Time-restricted eating is a dietary practice that involves eating 8 to 10 hours consistently within a narrow window of time and fasting for the remainder of the day. intermittent fasting is a form of this practice. a recent study published in the journal cell metabolism, conducted by researchers at the Salk Institute for Biological Studies in San Diego, has shown the potential benefits of time-restricted eating.

The study involved two groups of mice that were put on the same high-calorie diet. One group was only allowed to eat during a nine-hour window when they were most active, while the other group was allowed to eat whenever they wanted. After seven weeks, the mice on the time-restricted diet gained less weight than the control group, despite consuming the same amount of food.

To investigate the impact of the diet on the body, the researchers sacrificed two mice from each group every two hours over a 24-hour period. This allowed them to observe how the mice’s organ systems changed over time. The results showed that time-restricted eating led to “profound” changes in gene expression, with nearly 80% of all genes being impacted in some way. These changes resulted in a range of health benefits, including improved blood sugar regulation, decreased risk of obesity, and even a reversal of certain signs of aging.

The findings of this study suggest that time-restricted eating may be a powerful tool for preventing and managing a range of diseases, including obesity, diabetes, and cardiovascular disease. It may also provide benefits for gut function and cardiometabolic health. Further research is needed to confirm these findings in humans, but the results of this study provide promising evidence of the potential benefits of this dietary practice.

How time-restricted eating changes the body

A recent study published in the journal Cell Metabolism has shed new light on how time-restricted eating can change the body. Time-restricted eating involves eating consistently within a narrow window of time, usually 8 to 10 hours, and fasting for the remainder of the day. The study, conducted by researchers at the Salk Institute for Biological Studies in San Diego, involved two groups of mice that were put on the same high-calorie diet. One group was only allowed to eat during a nine-hour window when they were most active, while the other group was allowed to eat whenever they wanted.

After studying the mice’s organs, the researchers made a “pretty surprising” discovery: the mice on the time-restricted diet had synchronized their gene expression with their feeding schedules. This means that roughly 70% of all mouse genes fell into rhythm with the feeding schedule. When it was time to eat, individual organs were able to promote genes involved in nutrient metabolism and suppress those responsible for inflammatory signaling and immune activation. These changes led to a range of health benefits, including reduced inflammation, increased cellular housekeeping, improved RNA and protein balance, and more. The researchers believe that their findings may have implications for improving health and extending lifespan in humans.

The limitations

While the recent study published in the journal Cell Metabolism has shed new light on the potential benefits of time-restricted eating, it’s important to remember that these results were seen in mice, not humans. Dani Renouf is a registered dietitian at St. Paul’s Hospital in Vancouver, notes that we are still a long way off from demonstrating that the same phenomenon occurs in people. The experiments were also conducted in a tightly controlled environment, which may not accurately reflect the chaos and messiness of real life.

However, the lead author of the study, Shaunak Deota, believes that “most of these benefits can be translated to humans” because his lab’s findings align with what has been discovered in clinical studies on time-restricted eating in humans. For example, his findings on gene expression could explain why people who underwent the diet experienced greater insulin sensitivity, reduced total body mass, and lowered inflammation, according to a recent study in Nature Communications.

While more research is needed to confirm these findings in humans, the results of the study are a “wonderful start to a conversation” and provide promising evidence of the potential benefits of time-restricted eating. It’s important to continue conducting research and carefully evaluating the results before making any definitive conclusions about the effects of this dietary practice on humans.

Intermittent fasting according to age

Intermittent fasting has easily gained a lot of popularity in recent years as a way to improve overall health and wellness. But did you know that the way you approach intermittent fasting can vary based on your age? Here are a few interesting tips to help you find the proper and right intermittent fasting plan according to your age group:

For those in their 20s and 30s, the traditional 16/8 method, where you fast for 16 hours and eat during an 8-hour window, maybe a great option. This allows you to still enjoy a social life while reaping the benefits of intermittent fasting.

As we age, our bodies become more sensitive to changes in routine. For those in their 40s and 50s, a more flexible approach, like the 5:2 method, where you eat normally for 5 days and restrict calories to 500-600 for 2 non-consecutive days, may be more manageable.

For those over 60, it’s important to approach intermittent fasting with caution. Consult with a healthcare professional before starting any fasting plan and consider a modified version, such as the 6:1 method, where you eat normally for 6 days and restrict calories for 1 non-consecutive day.

No matter your age, it’s important to listen to your body and find the proper intermittent fasting plan that works best for you.

What we know works in weight loss

While the recent study on time-restricted eating has generated interest and excitement, Dani Renouf, a registered dietitian at St. Paul’s Hospital in Vancouver, approaches intermittent fasting and time-restricted eating with skepticism. Renouf notes that in the 20 years, she has been a dietitian, she has “never met a diet that works.” She believes that the studies on intermittent fasting have shown short-term results, but the long-term results are not convincing at this point.

For those looking to lose weight, Renouf recommends cutting down on alcohol consumption, increasing fiber intake from whole grains, fruits, and vegetables, and incorporating more movement into your daily routine. She emphasizes the importance of motivation and self-care in making positive changes for your health. Instead of comparing yourself to others, Renouf advises focusing on your own progress and celebrating any successes in taking care of yourself.

Helena

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